Landmark Pharma
Landmark Pharma
CBD Belapur, Mumbai, Maharashtra
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Anti Cancer Capsuls

Prominent & Leading Exporter from Mumbai, we offer lenvima capsule, tacrolimus capsule and tacrograf capsules.

Lenvima Capsule

Lenvima Capsule
  • Lenvima Capsule
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Product Details:

CompositionLenvatinib Capsules
Packaging TypeStrip
BrandElsai
Dose/Strength4mg/10mg
Form of MedicineCapsuls
Quantity Per Pack2x10 Capsuls

Uses:

This medication is used to treat kidney or thyroid cancer. Lenvatinib belongs to a class of drugs known as tyrosine kinase inhibitors. It works by slowing or stopping the growth of cancer cells.

 

How to use Lenvatinib Capsule:

  • Read the Patient Information Leaflet if available from your pharmacist before you start taking lenvatinib and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
  • Take this medication by mouth with or without food as directed by your doctor, usually once daily. Swallow the capsules whole. If you have trouble swallowing the capsules whole, place the capsules in a glass with a small amount of water or apple juice (1 tablespoon/15 milliliters). Let the capsules sit in the liquid for 10 minutes. Do not crush or break the capsules. After 10 minutes, stir the contents of the glass for at least 3 minutes. Drink all of the mixture right away. Then rinse the glass with another small amount of water or apple juice and drink the rinsing liquid to make sure you have taken the entire dose. Do not prepare a supply in advance.
  • The dosage is based on your medical condition, response to treatment, and laboratory tests.
  • Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.
  • Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of serious side effects will increase.
  • Since this drug can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the capsules.

Interactions:

  • Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

 

Side Effects:

Dry mouth, hoarseness, nose bleeds, tiredness, weight loss, headache, muscle/joint pain, trouble sleeping, change in taste, diarrhea, constipation, upset stomach, nausea, vomiting, or loss of appetite may occur. Nausea and vomiting can be severe. In some cases, your doctor may prescribe medication to prevent or relieve nausea and vomiting. Eating several small meals, not eating before treatment, or limiting activity may help lessen some of these effects. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Vomiting or diarrhea that doesn't stop may result in a serious loss of body water (dehydration). Contact your doctor promptly if you notice any symptoms of dehydration, such as unusual dry mouth/thirst, dizziness, or lightheadedness.

 

Precautions:

Before taking lenvatinib, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, high blood pressure, history of heart attack/stroke, loss of too much body water (dehydration).

 

Storage:

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

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Tacrolimus Capsule

Tacrolimus Capsule
  • Tacrolimus Capsule
  • Tacrolimus Capsule
  • Tacrolimus Capsule
  • Tacrolimus Capsule
  • Tacrolimus Capsule
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Product Details:

CompositionTacrolimus Capsules
Packaging TypeStrip
Packaging Size10 Capsules
BrandBiocon,Emcure,Panacea Biotec,Wockhardt Ltd,etc.
Usage/ApplicationPrevention of organ rejection in transplant patients

Indication:
indicated for organ transplant rejection prophylaxis. Patients are prescribed this medicine after an organ transplant, so as to help prevent the immune system from attacking the organ and to stop the body rejecting the transplant.


Mechanism of action:

Tacrolimus is a macrolide calcineurin inhibitor. In T-cells, activation of the T-cell receptor normally increases intracellular calcium, which acts via calmodulin to activate calcineurin. Calcineurin then dephosphorylates the transcription factor nuclear factor of activated T-cells (NF-AT), which moves to the nucleus of the T-cell and increases the activity of genes coding for IL-2 and related cytokines. Tacrolimus prevents the dephosphorylation of NF-AT. In detail, Tacrolimus reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP12 (FK506 binding protein) creating a new complex. This FKBP12-FK506 complex interacts with and inhibits calcineurin, thus inhibiting both T-lymphocyte signal transduction and IL-2 transcription. Although this activity is similar to that of ciclosporin, the incidence of acute rejection is reduced by tacrolimus use over ciclosporin. Although short-term immunosuppression concerning patient and graft survival is found to be similar between the two drugs, tacrolimus results in a more favorable lipid profile, and this may have important long-term implications given the prognostic influence of rejection on graft survival.


Dosage and Administration:

Oral tacrolimus is taken twice daily. Starting doses range between 0.075 mg/kg/day to 0.2 mg/kg/day. Doses vary widely and are based on tests that measure the amount of tacrolimus in the blood. Taking tacrolimus with food can reduce some of the abdominal pain that can occur with this medicine; however, food can reduce the amount of tacrolimus that is absorbed. This is especially true with fatty foods. Capsules should be taken consistently with or without food in order to avoid major swings in blood levels. Grapefruit juice increases blood levels of tacrolimus and should be avoided. The injection is only used for patients who cannot tolerate tacrolimus capsules.

Side effects:
Tacrolimus is associated with many and various side effects. These include:· baldness,anemia,loss of appetite,diarrhea,high concentrations of potassium in the blood,high blood pressure, nausea, vomiting, ,tingling sensation in the extremities, itching, tremor, fever, headache, rash, high blood sugar concentrations, and, abdominal pain.

Precaution:
An overdose Tacrolimus Unlikely to threaten life, call an emergency room or a poison control center for advice if you suspect that a very large dose of Tacrolimus has been ingested.There are no restrictions on food, beverages, or activities while taking Tacrolimus otherwise directed by your physician.


Store:
Tacrolimus is usually handled and stored by a health care provider. If you are using tacrolimus at home, store tacrolimus as directed by your pharmacist or health care provider. Keep tacrolimus out of the reach of children and away from pets.

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Tacrograf Capsules

Tacrograf Capsules
  • Tacrograf Capsules
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Product Details:

CompositionTacrograf Capsules
Packaging TypePacket
Packaging Size5X10 Capsules
BrandBiocon

Tacrograf (Tacrolimus) belongs to a group of medicines known as immunosuppressive agents. It is used to lower the body's natural immunity in patients who receive kidney transplants. When a patient receives an organ transplant the body's defense cells will try to reject the transplanted organ.
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Kumar Rupesh (CEO)
215, A Wing, Shiv Chamber, Plot No. 21, Sector 11, CBD, Belapur
Mumbai- 400614, Maharashtra, India



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